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Infectious Diseases
and STD-AIDS
Infectious Diseases and STD-AIDS 2018
Journal of Transmitted Diseases and Immunity
ISSN 2471-8084
A p r i l 2 6 - 2 7 , 2 0 1 8
R o m e , I t a l y
Page 39
Introduction:
Acquired Immunodeficiency Syndrome is a disease caused by
the Human Immunodeficiency Virus (HIV), with a major involvement of the
Thymus Cluster of Differentiation-CD4+ lymphocytes, leaving the organism
at the mercy of opportunistic infections such as renal failure, degeneration
of the central nervous system, microorganisms and parasites. As a focus of
one of the parasitic opportunistic infections, American trypanosomiasis can
be recognized, with the etiologic agent Trypanosoma cruzi, which has several
mechanisms of transmission. Immunosuppression in patients previously
infected by the parasite leads to the reactivation of the chronic disease, with
manifestations of exacerbation. HIV-infected individuals often demonstrate
secondary involvement of the brain by different infectious agents, and Chagas
disease is known as chagasic meningoencephalitis. In this condition, the
widening of the turns and narrowing of the brain grooves occurs, being observed
less assiduously, in the brainstem and in the cerebellum. Images provided by
magnetic resonance imaging (MRI) are better able to demonstrate structures
in the brain with minimal changes by exploring the regional and functional
anatomy of the brain in remarkably accurate details in most diseases. Among
the articles studied, the most common alteration was a hyper signal lesion in
TIME (T) 2 and fluid attenuation inversion recovery (FLAIR) and hypo signal
weights in T1 weights in the parieto-occipital region.
Objectives:
The objective is to demonstrate chagasic meningoencephalitis by
MRI in seropositive patients.
Methods:
A bibliographical survey was conducted in the Medline, PubMed
and Academic databases in 2015. The selection criteria used were articles
published in Portuguese and English.
Results:
Among the articles surveyed, four emphasized that the most common
alteration was a hyper signal lesion in T2 and FLAIR and hypo signal weights in
T1 weights in the parieto-occipital region.
Conclusion: Imaging diagnosis, particularly MRI, is the method most used
in clinical practice to evaluate meningoencephalitis in seropositive patients
because it presents a specific radiological signal.
Magnetic resonance imaging of chagasic meningoencephalitis
in HIV patients
Marcondes Juliana Scarlatte, Pinheiro Evelyn Albertini, Melo
Homero Jose de Frarias and Junior Luiz de Abreu
Sao Camilo University Center, Brazil
Marcondes Juliana Scarlatte et al., J Transm Dis Immun 2018 Volume 2
DOI: 10.21767/2573-0320-C1-003
Biography
Marcondes Juliana Scarlatte has completed her graduation
by Sao Camilo University Center (2016), qualified in imaging.
Postgraduate in Biomedicine in Diagnostic Imaging by Albert
Einstein Israel Institute for Teaching and Research (2018). Cur-
rently works at CURA Image and Diagnosis.
juh_scarlatte@hotmail.com