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Infectious Diseases
and STD-AIDS
Infectious Diseases and STD-AIDS 2018
Journal of Transmitted Diseases and Immunity
ISSN 2471-8084
A p r i l 2 6 - 2 7 , 2 0 1 8
R o m e , I t a l y
Page 38
Introduction:
Genital herpes is a dangerous obstetrical-neonatal disease.
Transmission can occur intra-uterinal, perinatal and postnatal. The infection
can be presented as a primary, non-primary first episode and recurrent episode.
Primary maternal HSV infection has higher risk of complications than recurrent
episodes. A high titer of maternal neutralizing antibodies is associated with
a lower risk of neonatal infection. Seroprevalence among pregnant women
varies between 7 and 33%. Transplacentarily acquired HSV infection before
20
th
week of pregnancy causes an increasing percentage of miscarriages or
multiple malformations.
Methods and Materials:
Reviewing of clinical monitored pregnancy and
childbirth with a recurrent HSV infection present and analysis of available
literature.
Results:
The first pregnancy of a 30 year old, at the time who had a genital
herpes in the early stage of her pregnancy ended bymedically indicated abortion
after 23 weeks of pregnancy because of multiple fetal malformations. Given
the patient's fear of the uncertainty of future pregnancies, detailed advicing
encouraged the pregnancy that followed after 3 and 5 years. The pregnancies
were intensively monitored clinically and serologically. Considering the HSV
IgM+ and prodromal symptoms at the end of the second pregnancy it was
completed by Caesarean section given the child's best interest. In the third
pregnancy, the patient was seronegative to HSV infection. From birth, 9/2015
the patient three times has developed clinically manifested herpes infection
of the genital area.
Discussion:
The decision to complete the pregnancy by Caesarean section
to prevent vertical transmission at the pregnant woman who had symptoms
of genital herpes, has resulted in a birth of a healthy child. The guidelines
recommend such a manner of childbirth also in those who have prodromal
symptoms with genital herpes in history. Pregnant women with a history of
reccurent genital herpes, from 36 weeks of pregnancy should be administered
antiviral prophylaxis.
Conclusion:
All pregnant women with the history of reccurent herpes simplex
infection should be closely monitored and treated according to the current
guidelines.
Herpes simplex virus 2 infection: Neglected, but serious issue
in pregnancy
Robert Vulic
Private practice in gynecology and obstetrics, Croatia
Robert Vulic Mashkani, J Transm Dis Immun 2018 Volume 2
DOI: 10.21767/2573-0320-C1-003
Biography
Robert Vulic is currently working under a private practice in gy-
necology and obstetrics, Split, Croatia
jairuashokb@gmail.com