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Infectious Diseases
and STD-AIDS
Infectious Diseases and STD-AIDS 2018
Journal of Transmitted Diseases and Immunity
ISSN 2471-8084
A p r i l 2 6 , 2 7 2 0 1 8
R o m e , I t a l y
Page 49
J Transm Dis Immun 2018 Volume 2
DOI: 10.21767/2573-0320-C1-003
Background:
An increased antibiotic resistance of bacterial isolates from wound infections is a major therapeutic challenge
for clinicians. The aim of this study was to describe bacterial isolates that caused wound infection and determine their current
antimicrobial susceptibility pattern.
Methods:
We analyzed the records of 380 wound swab samples that have been cultured at Bahir Dar regional health research
laboratory, Ethiopia from January 2013 to December 2015. Swabs from different wound types were collected aseptically.
Antimicrobial susceptibility test was performed using disc diffusion technique as per the standard protocol. Bacteriological and
socio-demographic data were collected using a standard data collection format. The data was cleared, entered and analyzed for
descriptive statistics using SPSS version 20.
Result:
The overall bacterial isolation rate in this study was at 61.6% (234/380). About 123 (52.6%) of the isolates were Gram
positive cocci and 111 (47.4%) were Gram negative rods. The predominant isolate was S. aureus at 100 (42.7%) followed by
E. coli 33 (14.1%), P. aeruginosa 26 (11.1%) and S. pyogenes 23 (9.8%). The overall rate of multidrug resistant (MDR) bacterial
pathogens that caused wound infection was 54.7%. Out of these, 35 (15.1%) of the isolates were resistant to more than five
antibiotics. Ampicillin had the highest resistance rate at 85.9% among Gram negative isolates. Whereas, the highest resistance
rate among Gram positive isolates was in Erythromycin at 31.1%.
Conclusion:
In the studied region, higher frequency of mono and multi drug resistance of bacterial pathogens that caused wound
infection was documented. Thus, a new method to the causative agent and antimicrobial susceptibility testing surveillance in
areas where there is no culture facility is needed to assist the health professionals in the selection of appropriate antibiotics.
deresehailu86@gmail.comDrug resistant pattern of bacterial isolates in
infected wounds at Bahir Dar Regional health
research laboratory center, northwest Ethiopia
Derese Hailu
1
, Awoke Derbie
2
, Daniel Mekonin
2
, wondmagegn
Mulu
2
, Yesuf Adem
2
, Alem Tsega
1
and Fantahun Biadglegne
2
1
Bahir Dar Regional Health Research Laboratory Center, Ethiopia
2
Bahir Dar University, Ethiopia