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Food Chemistry 2018 Journal of Food, Nutrition and Population Health
ISSN: 2577-0586 Page 86
July 23-24, 2018
Rome, Italy
3rd Edition of International Conference on
Agriculture &
Food Chemistry
J Food Nutr Popul Health 2018, Volume 2
DOI: 10.21767/2577-0586-C2-006
Ricebran,anagriculturalbyproductofwholegrainriceprocessing,
and cooked dry beans are globally accessible, complementary,
nutrient-dense functional foods that have evidence for prevention
of chronic and enteric infectious diseases. Based on data from
animal studies, we implemented and completed human dietary
intervention trials with these foods in infants, children, healthy
adults and colon cancer survivors using randomized controlled
trials.The feasibilityand tolerabilitywasshown for increasing intake
of rice bran and navy beans to levels that showbeneficial effects on
blood lipid regulation, the gut microbiome and stool metabolome.
Additionally, the integration of food and nutritional metabolomics
identified a number of prebiotics and phytochemicals that undergo
gut microbial biotransformation to influence gut immunity.
Microbiome was analyzed using 16S Illumina sequencing and the
blood, urine, and stool metabolome was analyzed using UPLC-
MS-MS. The effects of these foods on altered gastrointestinal
functions such as nutrient malabsorption and impaired immunity
that can affect normal growth and development will be shown. The
metabolite profiles depict changes in gut function across different
chemical classes in response to the foods, such as fatty acids,
primary and secondary bile acids and branched chain amino acids.
Maturity of the gut microbiota during infancy and weaning periods
are influenced by dietary patterns in a different manner than what
wesee inchildrenandadults.Thispresentationwill shareoutcomes
related to diarrheal disease and anthropometric measurements
in infant cohorts as well as modulation of the microbiome and
metabolome in children and adults after consuming rice bran and/
or navy beans. Funding support from the Bill and Melinda Gates
Foundation Grand Challenges Explorations in Global Health, the US
National Institutes of Health and US National Institutes of Food and
Agriculture was provided for these studies.
Dietary supplementation with rice bran and navy beans for gut
health and disease prevention across the lifespan
Elizabeth P Ryan
Colorado State University, USA