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Volume 4 Journal of Infectious Diseases and Treatment
ISSN: 2472-1093
Page 18
Euro Infectious Diseases 2018 &
Histopathology 2018
September 27-29, 2018
&
JOINT EVENT
September 27-29, 2018 Rome, Italy
5th International Conference on Histopathology & Cytopathology
10th Euro-Global Conference on Infectious Diseases
V I Petukhov et al., J Infec Dis Treat 2018, Volume 4
DOI: 10.21767/2472-1093-C1-002
Metal-ligand homeostasis of essential metals (Zn, Cu, Fe) in epidermis: Probable norm criteria
V I Petukhov1, Е V Dmitriev2, L Kh Baumane3, A V Skalny4, Yu N Lobanova4 and A R Grabeklis4
1Vladimir State University, Russia
2Institute of Numerical Mathematics - Russian Academy of Sciences, Russia
3Latvian Institute of Organic Synthesis, Latvia
4Centre for Biotic Medicine, Russia
The work is dedicated to the problem of the norm in the quantitative evaluation of metal content in the epidermal cells
(hair) obtained by the method of spectrometry. Authors have analyzed the hair samples for Zn, Cu, and Fe content, which
were obtained from 10000 healthy subjects (5000 males and 5000 females aged 20 to 45). The definition of the norm, in the
authors’ opinion, is closely related to the basic positions of the theory of self-organized criticality (SC). The observed shifts
in the homeostasis of essential metals are local and therefore cannot serve as a criterion of sufficient (or insufficient) metal
content throughout the body. The use of hair spectrometry for determination of metal content in epidermal cells has proven
to be ineffective in diagnostics of latent ID forms. However, the spectrometric analysis may be suitable for detecting criticality
(synchronization) as a normative (regulatory) criterion in the operation of membrane ATPases.
Biography
V I Petukhov was graduated from the Faculty of Therapy, 1st Leningrad Medical Institute and Post-graduation from Central Institute of Post-Diploma Education of
Physicians, Moscow. His Doctor’s field of specialization: Therapeutist – Hematologist. He has published more than 180 scientific works, including four monographs.
Presently, he is a Professor of the Vladimir State University, Vladimir, Russia, and Emeritus Professor of the Baltic International Academy, Riga, Latvia.