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Endocrinology 2018 Journal of Clinical and Molecular Endocrinology
ISSN: 2572-5432 Page 37
August 09-10, 2018
Madrid, Spain
11th International Conference on
Endocrinology and
Diabetology
Background: This research first hypothesis is that Cortisol, the
hormone in charge of sugar transfusion to the bloodstream to
handle stressful situations is what’s causing Alzheimer’s disease
because high levels of this hormone for prolonged periods of time
lead to deterioration of Secretases alpha beta and gamma, in
charge of the peptide of beta amyloid within the neurons. The 2nd
hypothesis is that Diabetics consumption of glucose also stems
from wanting to deter hyper cortisol secretion.
Methods: This research is a review of many studies showing
correlation between Alzheimer’s disease and Diabetes as
well as other illnesses (Hypertension, Cushing Syndrome and
Schizophrenia) with High Cortisol Levels, as well as low Vitamin
B12 and Folic Acid Levels and high levels of Homocysteine.
Results: In Alzheimer’s Diseases, Diabetes, Hypertension,
Schizophrenia and Cushing Syndrome, High Cortisol Levels as
well as Low Folic Acid and Vitamin B12 levels are evident
Conclusions:This proves true the hypotheses brought in the
background section regarding both AD and Diabetes to stem
from Cortisol secretion and basically from dealing with stress
and stressful everyday lives. What these finding suggest is that
a possible way of downgrading Cortisol Levels and preventing
or even treating said diseases is by maintaining a healthy diet of
folic acid and vitamin b12 and that deficiency of these vitamins
could possibly not only cause the above diseases but also to be
the cause of stress itself
Biography
Dr. Amos Gelbard is currently working in Zefat Academics Kibbutz Eilon, Is-
rael. His International experience includes various programs, contributions
and participation in different countries for diverse fields of study. Dr. Amos
Gelbard’s research interests reflect his wide range of publications in various
national and international journals.
Cortisol as the cause for several diseases and Folic Acid and
Vitamin B12 as possible therapeutic targets
Amos Gelbard
Zefat Academic College, Zefat, Israel
Amos Gelbard, J Clin Mol Endocrinol 2018, Volume 3
DOI: 10.21767/2572-5432-C2-005