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Volume 10

Journal of Archives of Medicine

Advanced Biotechnology & Annual Pediatrics 2018

November 28-29, 2018

Novel Trends and Advances in Biotechnology,

Cell & Stem Cell Research

Annual Congress on Pediatrics

World Congress on

November 28-29, 2018 Barcelona, Spain

Joint Event On

RegenerAge System: Therapeutic effects of combinatorial biologics (mRNA and allogenic MSCs)

with a spinal cord stimulation system on a patient with spinal cord section

Joel I Osorio

, Sergei Paylian

and Ale Ismael González Cazares

RegenerAge SAPI de CV, Mexico

Bioquark Inc., USA

Alive MD. Mexico

ioquantine® a mRNA extract from

Xenopus laevis

frog oocytes (purified from intra- and extra-oocyte liquid phases of

electroporated oocytes), showed potential as a treatment for a wide range of conditions in animal models, including Spinal

Cord Injury (SCI) and Traumatic Brain Injuries (TBI) among others. The current study observed beneficial changes with

Bioquantine® administration in a patient with severe SCI. Pluripotent stem cells have therapeutic and regenerative potential

in clinical situations CNS disorders. One method of reprogramming somatic cells into pluripotent stem cells is to expose

them to extracts prepared from

Xenopus laevis

oocytes. Due to ethical reasons and legal restrictions we selected a No Option

patient, deciding to include in our protocol the RestoreSensor SureScan to complete it. Based on the electrical stimulation

for rehabilitation and regeneration after spinal cord injury published by Hamid and MacEwan, we designed an improved

delivery method for the

in-situ

application of MSCs and Bioquantine® in combination with the RestoreSensor® SureScan®.

To the present day the patient who suffered a complete section of spinal cord at T12-L1 shows an improvement in sensitivity,

strength in striated muscle and smooth muscle connection, 14 months after the first Bioquantine® and MSCs treatment and 9

months after the placement.

Arch Med 2018, Volume 10

DOI: 10.21767/1989-5216-C2-006