Abstract

Many neuroprotective agents like donepezil hydrochloride has poor penetration to brain after oral/systemic administration due to poor permeation through blood brain barrier. Thus, it is required to develop a novel drug delivery system that would provide the release of neuroprotective agents/drugs directly into brain avoiding blood brain barrierMany neuroprotective agents like donepezil hydrochloride has poor penetration to brain after oral/systemic administration due to poor permeation through blood brain barrier. Thus, it is required to develop a novel drug delivery system that would provide the release of neuroprotective agents/drugs directly into brain avoiding blood brain barrier