Cancer is a genetic disorder in which the normal control of cell growth is lost. Cancer genetics is now one of the fastest expanding medical specialties. At the molecular level, cancer is caused by mutation(s) in DNA, which result in aberrant cell proliferation. Most of these mutations are acquired and occur in somatic cells. However, some people inherit mutation(s) in the germline. The mutation occurs in two classes of cellular genes: oncogenes and tumour suppressor genes.
Cancer Research, Journal of the National Cancer Institute, Clinical Cancer Research, International Journal of Cancer, European Journal of Cancer, Molecular Cancer Therapeutics, Molecular Cancer Research, Cancer Chemotherapy and Pharmacology, Current Cancer Drug Targets