A member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotic in the body. The CYP2 subfamily is responsible for the majority of P450-mediated drug metabolism in humans. While CYP2E1 itself carries out a relatively low number of these reactions and related enzymes CYP1A2 and CYP3A4 are responsible for the breakdown of a large number of toxic environmental chemicals and carcinogens that enter the body, in addition to basic metabolic reactions such as fatty acid oxidations.
Related Journals: Journal of Drug Metabolism & Toxicology, Journal of Pharmacokinetics & Experimental Therapeutics,Journal of Pharmacogenomics & Pharmacoproteomics , Journal of Bioequivalence & Bioavailability, Journal of Clinical & Medical Genomics, Pharmacogenomics Journal.
All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2018 All rights reserved. iMedPub LTD Last revised : September 21, 2018