Chiral Auxiliaries

A chiral auxiliary is a stereogenic group or unit that is temporarily incorporated into an organic compound in order to control the stereochemical outcome of the synthesis. chiral auxiliary can be used in a molecule when it doesnot contain a stereogenic centre. It allows enantioselective synthesis via diastereoselective reaction. If reaction is not diastereoselective, it act as a built in resolving agent. It can also be removed at a later stage. A wide variety of chiral auxiliaries are used to prepare amino acids such as oxzolidinones, aminoindanol, imidazolidones and pseudoephededrine.

Related Journals of Chiral Auxiliaries

RROIJ: Journal of Medicinal & Organic Chemistry, Organic Chemistry: Current Research, Research & Reviews: Journal of Pharmacognosy and Phytochemistry, Asymmetric Aldol Reaction Induced by Chiral Auxiliary, Modified Guanidines as Chiral Auxiliaries.

 

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