A chiral auxiliary is a stereogenic group or unit that is temporarily incorporated into an organic compound in order to control the stereochemical outcome of the synthesis. chiral auxiliary can be used in a molecule when it doesnot contain a stereogenic centre. It allows enantioselective synthesis via diastereoselective reaction. If reaction is not diastereoselective, it act as a built in resolving agent. It can also be removed at a later stage. A wide variety of chiral auxiliaries are used to prepare amino acids such as oxzolidinones, aminoindanol, imidazolidones and pseudoephededrine.
Related Journals of Chiral Auxiliaries
RROIJ: Journal of Medicinal & Organic Chemistry, Organic Chemistry: Current Research, Research & Reviews: Journal of Pharmacognosy and Phytochemistry, Asymmetric Aldol Reaction Induced by Chiral Auxiliary, Modified Guanidines as Chiral Auxiliaries.
All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2017 All rights reserved. iMedPub Last revised : June 22, 2017