Journal of Clinical and Molecular Endocrinology

Early improvement in metabolic surgery for obese polycystic ovary syndrome may be independent of the benefits of weight loss

4^th World Congress on Polycystic Ovarian Syndrome
June 07-08, 2018 London, UK

Jie Dai and Shen Qu

Tongji University, Shanghai, China

Posters & Accepted Abstracts: J Clin Mol Endocrinol

DOI: 10.21767/2572-5432-C1-003

Abstract

Aim: To investigate and discus the clinical curative effect of laparoscopic sleeve gastrectomy (LSG) on polycystic ovary syndrome (PCOS) . Methods: A retrospective analysis for the clinical data of 21 patients with PCOS accepted LSG in the Tenth People’s Hospital Affiliated to Tongji University from May 2013 to July 2017 was made to compare the changes of menstrual cycle, body weight, endocrine and inflammatory factors before and after 6 months operation. Results: 6 months after the operation, 90% patients recovered their normal menstrual cycle and ovulation. The shortest recovery period was two days and the average was (1.89 ± 1.286) months, and 1 patient recovered the fertility. The clinical data of 10 patients showed that canthosis nigricans were recovered, fasting blood glucose, glycosylated hemoglobin FBG, fasting insulin HbA1C FINS and HOMA-IR were significantly decreased (P<0.001), insulin sensitivity index IAI increased significantly (P<0.001), triglyceride TG decreased significantly (P<0.01), HDL increased significantly (P<0.001), uric acid UA significantly decreased(P<0.001)and testosterone T level decreased significantly (P<0.001).
Conclusion: LSG can decreased significantly improve the clinical symptoms of patients with PCOS which may be independent of weight and the change of Endocrinology and metabolism, and the mechanism needs to be further discussed. Metabolic surgery can be used as the effective treatment of patients with PCOS. Early improvement from metabolic surgery for patients with obese polycystic ovary syndrome may be independent of the benefits of weight loss.
 

Biography

Jie Dai is a postgraduate of Tongji University, resident physician, works in Youyi Community Health Center, Shanghai, China. She was selected in Baoshan medical personnel training program in the year 2015 and Tutor Shen Qu MD, PhD, professor, major in endocrine and metabolic diseases.

Email:251634656@qq.com