Peyronie's disease (PD), a condition of uncertain cause, is characterized by a plaque, or hard lump, that forms on the penis. The plaque develops on the upper or lower side of the penis in layers containing erectile tissue. Men with PD usually seek medical attention because of painful erections and difficulty with intercourse. Because the course of PD is different in each patient and some patients experience improvement without treatment, medical experts suggested waiting 1 to 2 years or longer before attempting to correct it surgically. During that wait, patients often are willing to undergo treatments whose effectiveness has not been proven. This review focuses on new developments for conservative treatment strategies for PD.
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