Role of Coxsackie virus B in Type 1 Diabetes-Brief Review

Diabetes is the chronic disease, which is known to develop due to the genetic autoimmune disorder leading to the destruction of the insulin producing β-cells or low production of insulin. Beside the role of the genetic factors in the genesis of the diabetes, other external environmental factors also known to be the cause. Studies revealed the association of the viral infection with the diabetes. Literature revealed the enterovirus mainly the Coxsackie virus has been found to be associated with the development of the diabetes. Studies showed the higher cellular immune response to the antigens of the Coxsackie virus B (CVB), at the onset of the diabetes. Experimental evidence of animal studies also favored the role of CVB. In the current scenario, we like to review the role and the presence of CVB in diabetic patients.

Author(s): Guru Prasad Manderwad

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