Urinary-tract-infection (UTI) is a major health/hygiene concern in the community with highest morbidity due to the fact of increasing multidrug-resistance in bacterial-uropathogens. Objective: Studies on prevalence of UTI in semi-urban Indian localities. Pattern study of antibiotic-resistance was investigated found in UTI. Aim was also to study the discrepancies in the sensitivity and resistant pattern of different pathogens against particular drug. Material & Methodology: Urine sample were collected (19-males/33-females) from Midnapore scan-center, West Bengal and analyzed. Result: The 40% of the UTI is attributed by E.coli followed by K. oxytocae (17%), Staphylococcus aureus (14%) (S.aureus). Female to male infection was 63:37(Figure-1a). The drug susceptibility response suggests that 70-100% of the bacterial isolates from the patients were susceptible to 26% of the drugs in case of E. coli, 36.66% in case of Klebsiella sp. and Enterrococci sp., 50% in case of Citrobacter sp. 53.33% of the drugs in case of S.aureus and 73.33% in case of Proteus sp. Conclusion: E. coli is resistant to most of the drugs. Drug-sensitivity pattern of individuals suggests that when a larger number of drugs behave sensitively against Citrobactor sp. in more number of patients, a small number of drugs are sensitive to S. aureus in in more number of patients.