Piperonyl Butoxide: An Enhancing Arsenal for an Adomant Foe

Vector control using treated nets and recently industrially long lasting insecticidal nets (LLINs) have played a vital role in malaria control globally. The emergence of insecticides resistance among malaria vector against pyrethroids has raised a concern over achieved a milestone. Different insecticides resistance mechanisms have evolved against pyrethroids. This has given mosquitoes an opportunity to increase survivor fitness. The incorporation of synegistic effect of Piperonyl Butoxide (PBO) in LLINs has shown a significant impact in areas with pyrethroid resistant malaria vectors than LLIN without PBO. LLINs with PBO for management of resistance can revive pyrethroid strength against resistant malaria vectors. There is a necessity for National malaria control and other NGOs in Africa distributing LLINs to distribute nets with pyrethroids and PBO.

Author(s): Kweka EJ, Mazigo HD, Mapunda G and Yewhalaw D

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