Lettuce is one of the most abundant leafy vegetables and is consumed in its raw form by humans, all over the world. This study was conducted in one of the fields in the district of Al-Garmah City, Iraq to know the effect of some of the fertilizer (Animal, Chemical, and Compost fertilizer). The crop of lettuce for August 2017 to March 2018 used class Paris Island and was a two-stage experience. The experiment was carried out in two stages. The first phase included the multiplication of the earthworm and the production of the worm (vermicompost). The second phase included the cultivation of lettuce in three replicates with ten coefficients and additions of animal fertilizer, vermicompost, chemical fertilizer (NPK). The results shows that the highest productivity was the lettuce plant in vermicomposts second with level recommendation half of the fertilizing, and second-ranked vermicompost only the second level and was the third place in the recommendation vermicompost 1/2 second with level waste sheep 1/2 second level. The following percentages were then obtained sequentially (T5), (T8), (T3), (T9), (T7), (T2), (T1). Through the results of the experiment we conclude that the production of vermicomposts for being environmentally and hygienically and resulting crops are more healthy for the consumer. More research is needed to fully understand the ecology of different earthworm species, their interactions and their potential roles in promoting more sustainable farming systems.