Ayman I. SayeghProfessor, Associate Dean for Research and Advanced Studies, College of Veterinary Medicine, Williams-Bowie Hall 101, Clinical Anatomy 204, Tuskegee, Alabama 36088, USA
Biography
Dr. Sayegh is a Professor of Biomedical Sciences,
College of Veterinary Medicine, Tuskegee University
and Associate Dean for Research and Advanced
Studies. He attended Baghdad University (Iraq,
Veterinary Medicine), Kansas State University (MS),
Purdue University (Equine Medicine and Surgery),
University of Illinois at Urbana Champaign (Equine
Medicine and Surgery) and Washington State
University (PhD, Neuroscience). His research focuses
on localizing the peripheral site(s) of action for
gastrin releasing peptide (GRP) and cholecystokinin
(CCK), which evoke reduction of meal size and
prolongation of the intermeal interval, by delivering
the peptides into specific regions in the
gastrointestinal tract through (1) utilizing a
microsurgical, intra-arterial catheterization technique,
(2) analyzing the min-to-min behaviors that lead to
feeding to determine meal sizes, intermeal interval
and satiety ratio, (3) using a BioDAQ feeding system
to record and analyze the feeding behavior of the rats
in a freely-fed, undisturbed environment. In addition,
we use immunohistochemical detection of neuronal
markers and various surgical techniques e.g.
vagotomy, sympathectomy and myotomy /
myectomy to determine the possible neuronal
pathways by which these peptide reduce meal size
and prolong the intermeal interval. The work is
funded by the NIH and various pharmaceutical
companies
Research Interest
His research focuses on localizing the peripheral site(s) of action for gastrin releasing peptide (GRP) and
cholecystokinin (CCK), which evoke reduction of meal size and prolongation of the intermeal interval, by delivering
the peptides into specific regions in the gastrointestinal tract through (1) utilizing a microsurgical, intra-arterial
catheterization technique, (2) analyzing the min-to-min behaviors that lead to feeding to determine meal sizes,
intermeal interval and satiety ratio, (3) using a BioDAQ feeding system to record and analyze the feeding behavior
of the rats in a freely-fed, undisturbed environment. In addition, we use immunohistochemical detection of neuronal
markers and various surgical techniques e.g. vagotomy, sympathectomy and myotomy / myectomy to determine the
possible neuronal pathways by which these peptide reduce meal size and prolong the intermeal interval. The work is
funded by the NIH and various pharmaceutical companies.