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World Nutrition 2018
J u n e 1 8 - 1 9 , 2 0 1 8
P a r i s , F r a n c e
Page 26
Journal of Clinical Nutrition & Dietetics
ISSN 2472-1921
W o r l d C o n g r e s s o n
Nutrition and Dietetics
Despite achieved progress in the control and treatment of pregnant women with gestational diabetes mellitus (GDM), these
patients are still at risk of disease complications. The aim of present study was to investigate the effect of probiotic supplement
on systolic blood pressure (SBP) and diastolic blood pressure (DBP) among GDM pregnant women. In this randomized double-
blind, placebo-controlled trial, 64 pregnant women with GDMwere assigned into two groups and received probiotic capsule (n=32)
or placebo (n=32) for 8 weeks. Blood pressures were measured at baseline, 2 weeks intervals and up to 8 weeks. 56 subjects
were analyzed at the end of the study. After 8 weeks, SBP didn’t differ significantly in probiotic group at any time checkpoint
but increased significantly in placebo group. DBP changes in a trend in probiotic group was obvious after 2 weeks and was
reducing towards, however in placebo group, there was a tendency for higher DBP after week 6. There were significant differences
between two groups of study after 6 weeks in the terms of SBP [104.828 (2.051) mmHg vs. 112.963 (2.126) mmHg, p=0.008 and
106.552(1.845) mmHg vs. 115.185 (1.912) mmHg, p=0.002, in week 6 and 8 respectively] and DBP [62.414 (1.353) mmHg vs.
70.741 (1.402) mmHg , p<0.001and 60.690 (1.540) mmHg vs. 71.296 (1.596) mmHg, p< 0.001, in weeks 6 and 8 respectively].
Conclusion:
The results demonstrated that taking probiotic supplements for 8 weeks in patients with GDM prevented the increase
of SBP and resulted in reduction of DBP after 2 weeks of consumption
Biography
Majid Hajifaraji is a Research Associate, Professor in Nutritional Sciences of the National Nutrition and Food Technology Research Institute (NNFTRI), and has served as Dean of
Faculty of Nutritional Sciences and Food Technology (FNSFT) from 2010- 2015 and President of Iranian Nutrition Society (INS) from 2011-2015. He has a PhD in Clinical Nutrition
program at Kings College, London University.
m39faraji@yahoo.comWhether probiotic supplementation is effective in prevention of the
hyperglycemia induced maternal hypertension?
Majid Hajifaraji
1
, Neda Dolatkhah
2
, Fatemeh Abbasalizadeh
2
and Naser Aghamohammadzadeh
2
1
Shahid Beheshti University of Medical Sciences (SBUMS)/ National Nutrition & Food Technology
Research Institute (NNFTRI), I.R. Iran
2
Tehran University of Medical Sciences, Iran
Majid Hajifaraji et al., J Clin Nutr Diet 2018 Volume: 4
DOI: 10.4172/2472-1921-C1-002
Changes in the Systolic blood pressure over
the time points in each group
Changes in the Diastolic blood pressure over
the time points in each group