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Structural Biology 2018
Volume: 4
Biochemistry & Molecular Biology Journal
Page 50
March 15-16 2018
Barcelona, Spain
10
th
Edition of International Conference on
Structural Biology
T
he
5-(1,5diamino-pentyl)-1-amino-1H-1,3,4-triazole-2-thiol
[1]
and the 5-(1,5 diamino-pentyl)-4-amino-S-glucosyl-1,2,4-
triazole
[2]
derivatives form amino acid were synthesized. The
synthetic intermediates, ester, hydrazid and and thiosemicarbazide
derivates have show a significant tendency to form S-Nucleosides
with sugar (glucose). A novel nucleoside from oxadiazol the
derivative with glucose was synthesized and was detected by
IR spectroscopy and NMR
[3]
. The antimicrobial activity for final
and synthetic intermediates
in vitro
against the microorganisms:
Echerichia coli
,
Pseudomonas aeruginosa
,
Staphylococus aureus
and
Salmonelle chiguer
were examined and some products
showed noticeable activity against the tested miroorganisms
[4]
.
References:
1. Z. Khiati, A. A.Othmane. Chem. Sci Trans. 1 (2012) 185-
193.
2. Y. Datoussaid
et al.
S.AFR.J. Chem. (2012) 65.
3. J.E.Mangette,
et al.
Tetrahdron. 65 (2009) 9536-6541.
4. S.Benhammadi,
et al.
Asian J Chem. (2010) 5535-5542
Biography
Yamina C has completed her PhD at the age of 32 years fromOran Universi-
ty, ALGERIA. She is the student of Mostaganem University, Algeria. She has
one publication on journal of European Chemical Bulletin “Synthesis and
Antimacrobial Activity of Some New L-Lysine Glycoside Derivatives”.
chergui.amina@yahoo.frAntimacrobial Activity and Synthese Of Thiosemicarbazide
Amino Acid Derives
Yamina C
University of Mostaganem, Algeria
Yamina C, Biochem Mol biol J, Volume 4
DOI: 10.21767/2471-8084-C1-009