osteoporosis-arthroplasty-2017-scientifictracks

25 / 29

Page 49
Volume 3, Issue 4 (Suppl) J Clin Exp Orthop
ISSN:2471-8416 Osteoporosis and Arthroplasty 2017
December 04-05, 2017
&
11th International Conference on
Joint Event
OSTEOPOROSIS, ARTHRITIS & MUSCULOSKELETAL DISORDERS
December 04-05, 2017 | Madrid, Spain
10th INTERNATIONAL CONFERENCE ON ARTHROPLASTY
Monitoring of metastatic bone tumor using by near-infrared fluorometric imaging system on mouse
xenograft model
Wonbong Lim
Chosun University, South Korea
Tumors of the prostate or breast are particularly likely to metastasize to the bone, and early diagnosis of metastatic bone tumors
is important for designing an effective treatment strategy. Imaging modalities for the detection of bone metastasis are limited,
and radiation-based techniques are commonly used. Here, we investigated the efficacy of selective near-infrared (NIR) fluorescence
detection of metastatic bone tumors and its role in the detection of bone metastasis in prostate and breast cancer cell lines and in a
xenograft mouse model. A targeted NIR fluorophore was used to monitor metastatic bone tumors using a NIR fluorescence imaging
system in real time, enabling the diagnosis of bone metastasis in vivo by providing the location of the metastatic bone tumor. The NIR
fluorescence imaging technique using targeted NIR contrast agents is a potential tool for the early diagnosis of bone tumors.
Biography
Wonbong Lim has completed his PhD from Department of Oral Pathology at Chonnam National University in South Korea and Postdoctoral studies from same
place. He is the Assistant Professor in Department of Premedical Science, College of Medicine, Chosun University and Director of research lab at Department
of Orthopaedic Surgery in Chosun University Hospital. He has published more than 50 papers in reputed journals including Bone Biology and Carcinogenesis.
Wonbong Lim, J Clin Exp Orthop 2017, 3:4(Suppl)
DOI: 10.4172/2471-8416-C1-002