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Page 58

J Obes Eat Disord, 2017

ISSN: 2471-8203

August 23-24, 2017 | Toronto, Canada

allied

academies

INTERNATIONAL OBESITY, BARIATRIC AND

METABOLIC SURGERY SUMMIT AND EXPO

J Obes Eat Disord, 3:2

DOI: 10.21767/2471-8203-C1-003

Background:

Overweight and obesity are strongly associated

with the development of several chronic diseases in human

including diabetes, cardiovascular disease and high blood

pressure. Flax seed is known as an effective compound for

treatment of obesity due to high content of alpha-linolenic

acid, fiber and lignans.

Objective:

We aim to evaluate the effects of flaxseed

consumption on serum adiponectin, leptin, and weight loss

in overweight or obese women.

Methods:

Arandomizedcontrolledclinicaltrialwasconducted

on 60 patients with overweight or obesity. Participants were

randomly allocated to two groups; a) weight loss diet plus

25 g/day brown milled Flaxseed and b) weight loss diet plus

25 g/day raw powder rice, for 12 weeks. Anthropometric

indices and serum leptin and adiponectin were measured at

baseline and at the end of the intervention.

Findings:

After 12 weeks of intervention, weight, body

mass index (BMI) and waist to hip ratio (WHR) decreased

significantly in flaxseed group but not the controls. Reduction

of waist circumference (WC) (P=0.001) and WHR (P=0.003)

were significantly more in flaxseed group compared to

control group. There was a significant reduction in serum

leptin and an increase in serum adiponectin of flaxseed

group after intervention (P<0.001 for both). Increase of

adiponectin level was significantly more in flaxseed group

compared to the controls (P=0.002).

Conclusion:

Flaxseed consumption could reduce WC and

WHR in a low energy diet. Also it may improve adiponectin

level as an important adipocytokine in regulation of body

composition and weight. So, flax seeds can be used as a

supplement to attenuate central obesity.

e:

shivafaghih@gmail.com

Flaxseed consumption could improve adiponectin level and reduce central obesity in overweight or

obese women: A randomized controlled clinical trial

Shiva Faghih and Hoda Ahmadnia

Shiraz University of Medical Sciences, Iran