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Volume 05
Journal of Clinical Nutrition & Dietetics
ISSN: 2472-1921
JOINT EVENT
June 17-18, 2019 London, UK
Nutrition World 2019
Euro Obesity 2019
June 17-18, 2019
&
26
th
World Nutrition Congress
15
th
Euro Obesity and Endocrinology Congress
FADS gene polymorphisms modulate the association between dietary n-3 LCPUFAs and DHAproportion
in breast milk
Wen-Chieh Wu
and
Pei-Min Chao
China Medical University, Taiwan
D
HA is important for the development of brain and retina in newborns. Considering that exclusive breast
feeding for atleast 4-6 months are globally recommended, plus it is well known that nutrient requirement is
determined by both genetic and environmental (including diet) factors, this clinical study was sought to investigate
how the DHA levels in maternal milk is modulated by genetic variants and dietary n-3 LCPUFA intake. To recruit
subjects (n=193), the inclusion criteria are Han Chinese women just having delivered full-term baby, 20-40 years old,
healthy and willing to breast feed their baby for atleast two months. Written informed consent will be obtained from
participants. Personal information (or covariates) such as height, weight (before getting pregnancy and delivery,
respectively), age, parity, education, smoking, alcohol drinking, gender of baby etc., and DNA from oral swab will
be collected. Breast milk and dietary data will be collected at the end of the 1
st
and 2
nd
month of postpartum period.
Considering Han Chinese women usually have special postpartum diets and care during puerperium. Therefore,
collection of breast milk and dietary information will be repeated at the 2
nd
month. The fatty acid composition in
milk will be analyzed by gas chromatography. Using food frequency questionnaire, intake of n-3 LCPUFA from
foods and fish oil supplements will be calculated. We foresee that results of this study might contribute to public
health care as nutritionists/dietitians will be able to target the vulnerable subjects, who are dietary dependent for
DHA, for dedications in nutrition consults or customized dietary guidance. Moreover, this information is valuable
in making policy regarding dietary recommendation in Taiwan.
Biography
Wen-Chieh Wu is a PhD student of Nutrition at China Medical University since 2013. His work focuses specifically on precision nutrition of pregnant and
postpartum women. In addition, he has collaborated with company to develop genetic testing products and personalized meal services.
willson60805@gmail.comWen-Chieh Wu et al., J Clin Nutr Diet 2019, Volume 05