9 / 35
Infectious Diseases 2018
Journal of Prevention and Infection Control
ISSN: 2471-9668
Page 47
June 07-08, 2018
London, UK
8
th
Edition of International Conference on
Infectious Diseases
Background:
A febrile man, who returned to China after a nine-day
travel in Fiji and Samoa, was detected to be infected with Zika virus
(ZIKV) at the port by Shenzhen Entry-Exit Inspection andQuarantine
Bureau on Feb 14, 2016.
Methods:
The patient and his 32 travelling companions were
traced for ZIKV infection. A standardized questionnaire was used
to obtain the information on demographics, clinical manifestations
and exposure history. Their samples were tested for ZIKV by
quantitative reverse transcriptase polymerase-chain-reaction (qRT-
PCR). The positive samples were subjected to viral culture and
genome sequencing.
Findings:
Four of the 33 travelers were confirmed to be infected by
ZIKV through qRT-PCR and viral culture, with an overall infection
rate of 12%. Interestingly, one case (patient 3) had high viremia
levels and was tested four days prior to symptoms. In addition,
a 7-year-old girl was identified to have ZIKV infection on Feb 17,
but never had any manifestation. ZIKV was isolated from the four
imported cases. Phylogenetic analysis based on whole genome
sequences revealed that these isolates were similar to each other
and close to the strain causing the French Polynesia outbreak in
2013.
Interpretation:
The travelers should be informed of the high risk for
ZIKV infection during their stay in areas with active transmission,
and measures to prevent mosquito-bites.
Biography
Runzi Qi is a Medical Doctor (MD), Deputy Director of Health Quarantine, Former Zheji-
ang Entry-Exit Inspection and Quarantine Bureau until May 2018. Now Deputy Director
of Health Quarantine, Hangzhou Customs District People’s Republic of China.
qrz@ziq.gov.cnA cluster of Zika virus infection among travelers returning to
China from Samoa: a case tracing study
Runzi Qi
1
, Wei Zheng
1
, Sheng Zhu
2
, Zhonghua Wu
1
, Tommy Tsan Yuk Lam
3
, Yuanhua
Tong
2
and
Gang Wang
1
1
Zhejiang Entry-Exit Inspection and Quarantine Bureau, China
2
Yiwu Entry-Exit Inspection and Quarantine Bureau, China
3
State Key Laboratory of Emerging Infectious Diseases – HKU, China
Runzi Qi et al., J Prev Infect Cntrol 2018, Volume 4
DOI: 10.21767/2471-9668-C1-003