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E u r o p e a n C o n g r e s s o n
Vaccines & Vaccination
and Gynecologic Oncology
Vaccines & Vaccination and Gynecologic Oncology 2018
O c t o b e r 2 6 - 2 7 , 2 0 1 8
B u d a p e s t , H u n g a r y
Critical Care Obstetrics and Gynecology
ISSN: 2471-9803
Biography
Charulata has completed her PhD and she is senior consultant
embryologist at Yashoda Fertility and Research Institute,
Hyderabad, India. She has a 18 long years experience in field
of ART. She keeps herself updated with recent advances
in ART and regular in writing Abstracts, Posters, Oral paper
presentations in national and international forum.
charulata88@gmail.comDouble homologous IUI with combination of two sperm
preparation method to improve pregnancy outcome
Charulata Chatterjee and Laksmi Krishna Leela
Yashoda Fertility and Research Institute, India
Background:
Intra uterine insemination (IUI) is preferred fertility treatment for
unexplained and moderate male factor sub fertility. Incorporation of double
insemination and two sperm preparation method (double density gradient and
swim up) might help to improve outcome.
Purpose:
This study aims to investigate the single vs. doubles IUI in controlled
ovarian hyperstimulation cycle (COH) and to evaluate the effects of combining
two methods on improving the efficacy of sperm preparation.
Design:
Retrospective study
Setting:
A newly opened private fertility institute
Patients:
41 couples undergoing COH for an IUI cycle within three months of
institute inauguration.
Main outcome measure:
The primary outcome measure was clinical pregnancy.
Methods:
Inclusion criteria for women were age below 35 years with functional
fallopian tube/s and no other noted uterine or ovarian abnormalities. Men with
post-wash total motile sperm count of at least 10 million were included in the
study. All women underwent COH and ovulation tracking was done with ultra
sound scan. Inseminations were performed either once or twice depending upon
ovulation status or as decided earlier with couples. In case of double IUI density
gradient processed sperm were inseminated in pre ovulatory phase and sperms
were processed through swim up technique and then inseminated after ovulation.
Results:
Out of 41, one couple dropped the treatment in between due to personal
reason and 22 couple underwent double IUI whereas 18 couple single IUI was
done. The overall clinical pregnancy rate was 22.72% and 11.11% (p=0.3424) for
double vs. single IUI respectively.
Conclusion:
A combination of two sperm preparation methods resulted in higher
recovery rates of mature motile spermatozoa and helped to improve success rate.
A large group study is recommended to support this observation.
Charulata Chatterjee et al., Crit Care Obst & Gyne 2018, Volume: 4
DOI:10.21767/2471-9803-C1-002