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Volume 3, Issue 4 (Suppl)
Polym Sci
ISSN: 2471-9935 Polym Sci, an open access journal
October 12-13, 2017 Osaka, Japan
Annual Meeting on
Biopolymers and Drug Delivery Systems
Biopolymers Meeting 2017
October 12-13 2017
Page 64
Polym Sci 2017, 3:4
DOI: 10.4172/2471-9935-C1-006
Formulation and pharmacological evaluation of metallic nanoparticles
M Sunitha Reddy
Jawaharlal Nehru Technological University, India
I
n recent research and development there has been prodigious excitement in the nano pharmacological area for the study of
nanoparticles synthesis using some natural products. Biological methods have been used to synthesize zinc oxide nanoparticles
in presence of medicinally active plants such as
Ocimum tenuiflorum, Azadirachta indica
, etc., and this intention made us to assess
the biologically synthesized zinc oxide nanoparticles from the leaf of
Ocimum tenuiflorum
using 1 mM zinc oxide solution. Zinc
oxide nanoparticles have been widely used for many applications. In current study the nanoparticles tested for their anti-diabetic
activity. Morphology and metal composition of synthesized nanoparticles were determined by characterization techniques. Poly
herbal formulation was prepared by proper addition of plant mediated zinc oxide nanoparticles that were prepared from
Ocimum
tenuiflorum
and
Azadirachta indica
. The formulation tested for its in vitro anti diabetic activity using α-amylase assay. The strongest
activity (at concentration: 25 mg/ml) was shown by the nanoparticles formulation (97.77%) comparatively with crude extract. The
outcomes of this study show that the administration of some of metallic nanoparticles may possibly control the postprandial blood
glucose ranges and confirm the use of these herbs suggested as a treatment of diabetes in traditional medicine and displayed a good
inhibitory activity on amylase.
baddam_sunitha@rediffmail.com