Antonio J Costa-Filho Associate Professor |
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Biography | ||
Antonio Jos̮̩ da Costa Filho received a Bachelor degree in Physics from the University of S̮̣o Paulo (USP) in 1994. After that he started his graduate program in the same university, concluding his Masters in 1996. His PhD project was developed both in S̮̣o Carlos (Brazil), under the supervision of Prof. Otaciro Nascimento, and in Ithaca (USA), where he spent 3 years as a graduate student at Cornell University, working under Prof. Jack Freed̫̉s supervision. During his PhD, Prof. Antonio Costa worked on the development of new electron magnetic resonance methods for the study of: (1) lipid-protein interactions, (2) the dynamic structure of lipid membranes, and (3) metal centers in protein structure. In 2001 he received his PhD degree in Physics from the University of S̮̣o Paulo and started working as an Assistant Professor at USP (Campus S̮̣o Carlos). He is currently a Full Professor at USP-Ribeir̮̣o Preto and his research interests involve the investigation of interactions between biomolecules with emphasis on how the interaction between proteins and their ligands (substrates, inhibitors, and membranes) can lead to modulation/control of the protein function. More recently, he also got involved in projects seeking to identify how pharmacologically-relevant compounds (metal complexes and drugs) affect the organization of models for the cell membrane. To accomplish those objectives he makes use of a combined and interdisciplinary approach of experimental techniques such as magnetic resonance, circular dichroism, and microcalorimetry. In this context, Prof. Costa-Filho group has been pioneering the establishment of electron magnetic resonance methods in Brazil for the study of conformational changes in proteins, such as site-directed spin labelling and double electron-electron resonance (DEER). He has received several awards for his teaching skills as well as for contributions to his specific field of scientific interest. He is an Affiliate Member of the Brazilian Academy of Sciences, an Affiliate Member of the Academy of Sciences for the Developing World (previous Third World Academy of Sciences ? TWAS), and a research fellow (1C) of the Brazilian Research Council (CNPq). | ||
Research Interest | ||
Molecular Biophysics, Pulsed electron spin resonance, Lipid-Protein Interactions, Metalloproteins | ||
Global Experts in the subject | ||
A. Jeyakumar | Abdulaziz A. Zorgani | Abdulaziz Zorgani |
Adriana Fernandes da Silva | Altaf Hussain | Amalesh Samanta |
Anand Kumar Meka | Andrea S Torrïÿýo | Arasambattu K Mohanakrishnan |
Arthi Chandran | Arun Kumar | Asha K K |
Astha Nigam | Avnish Kumar | B Raghu |
Balakrishnan T | Baoguo Sun | Belgherbi A. |
Belokoneva EL | Brandon Quillian | Bubbly SG |
Carlos J Gomez-Garcia | Caroline Huber Rosa | Chao-Chia Weng |
Chen-Tin Liu | Chen-Yuan Hsiao | Cheng-Hsi Su |
Chetan Shripanavar | Chi-Ming Wu | Chia-Hsin Pan |
Chia-Yu Wu | Ching-Zong Wu | Clifford W Padgett |
Cristina Vallis-Garcia | D. Ghosh | Deepak Chopra |
Dimitrova OV | Dr Aruna Kumari R | Dr Navin Gupta |
Dr P.S. Pawan Kalyan | Dr Prabhavati | Dr Suma H.R |
Dr. Iyshwarya U | Eduardo Kremer | Elizabeth Une Amuta |
Evandro Piva | Farzeen Tanwir | Federico Leonardo Motta |
G. Sivaradje | Gabriela Kramer M | Gaurav Gupta |
Gianella Facchin | Govind Rai Garg | Hadassa Batinga |
Hadjidj I. | Han-Yi Cheng | Hans-Jorg Schanz |
Hatem belguith | Heng-Jui Hsu | Heyam Y. Abello |
Hiremath Doddayya | Hoda M Hassab | Hongyu Qiao |
Hsi-Jen Chiang | Hsiao-Huang Chang | Huijuan Zhang |
Hwai-Shi Wang | I Samanta | Imoh Okon |
Jagadale Sachin K |