Archives in Cancer Research

Laboratoire d’Anatomo-Pathologie, Centre Hospitalier Universitaire de Nice, Hôpital Archet , Nice, France

Anne Chevalier being an eminent members at Laboratoire d’Anatomo-Pathologie, Centre Hospitalier Universitaire de Nice, Hôpital Archet , Nice, France and have a great interest towards Journal and has worked for more than 10 years in the related field and gained a loads of knowledge in related field. His/Her working has been displayed at the international conferences and been published in journal proceedings.

Type-Specific Human Papillomavirus Testing for the Follow-up of Women with a Typical Squamous Cells of Undetermined Significance (ASCUS) Pap Smears

Background: The aim of our study was to assess the prevalence of Human papillomavirus (HPV) genotypes amongst women diagnosed with Atypical Squamous Cells of Undetermined Significance (ASC-US) Pap smears in southern France and to determine whether the systematic application of HPV genotyping in this patient population could improve the ability to identify women with a higher or lower risk of progression to cervical cancer or CIN2 or 3. The ultimate goal is to limit the number of colposcopy performed unnecessarily in women with ASC-US cytology.

Methods: We performed a retrospective study of HPV genotype distribution in 313 ASC-US Pap smears from women who attended at the University Hospital of Nice between 2008 and 2012. We analysed by logistic regression the progression of cervical lesions correlating with the genotypes identified.