Archives in Cancer Research

Department of Imagery and Radiology, C.I. Parhon National Institute of Endocrinology, Bucharest, Romania

Anda Dumitrascu being an eminent members at Department of Imagery and Radiology, C.I. Parhon National Institute of Endocrinology, Bucharest, Romania in Romania have a great interest towards Journal name and  has worked for more than 10 years in the related field and gained a loads of knowledge in related field. His/Her working has been displayed at the international conferences and been published in journal proceedings.

Bone Loss as Sign of Cancer Relapse

There is a tacit assumption that cancer cell lines removed from incubation and tumors that grow from the injection of these cells into mice diminish vitality quickly. When the melanoma tumors (from about 1 million B16-BL6 cells injected within 1 hr after removal from incubation) were removed about three to four weeks later and placed over the sensors of photomultiplier tubes conspicuous ~40 min periodicities of photon emissions began between 24 to 48 hr later. One million cells extracted from 10 cc suspensions of (~108) mouse melanoma cells that remained at room temperature for up to 3 days (when the smell was fetid) still produced viable tumors when injected subcutaneously. The tumors were more aqueous than those produced from immediately injected cells and were similarly fetid upon dissection unlike typical melanoma tumors. Their histopathology was qualitatively different. These results indicate that aggregates of cells in suspension or as tumors show unexpected properties that should be accommodated in models of proliferation and growth for malignant cells.