Santosh Misal

Santosh Misal
Department of Chemistry, Indiana University, Bloomington, USA


I have completed Masters and PhD degree in Biochemistry at Savitribai Phule Pune University in India. I completed my first postdoctoral research training at University of Montreal and McGill University affiliated Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Canada. Then I moved to Indiana University, Bloomington as a Postdoctoral Research Associate. My PhD work was focused on the isolation, purification and biochemical characterization of Azoreductase/Nitroreductase enzymes involved in bioremediation of xenobiotics. As a postdoctoral fellow at IRCM, Canada, I studied the centrosomal proteins over-expressed in various ciliopathies and cancer. At Indiana University Bloomington, I am working on multiple projects including chemical labeling and crosslinking of proteins to map the protein-protein interaction sites by mass spectrometry. We are also investigating the toxins secreted by S. aureus bacteria and their secretory pathways.

Research Interest

My current research interest mainly includes identification, biochemical and structural characterization of novel bacterial ribosome associated proteins and enzymes involved in protein synthesis. Also, I am studying the secretory proteins from S. aureus and their secretory pathways.