Mohammed TariqueInternational Centre for Genetic Engineering and Biotechnology (ICGEB),
Biography
Currently Dr. Tarique is working as Post-doctoral Research Associate in the Parasite cell biology group at International Center for Genetic Engineering and Biotechnology, New Delhi. He did his B.Sc. (Chemistry and Botany) in 2006 from Shibli National College, Azamgarh, UP and M.Sc. (Biotechnology) in 2008 from the department of biotechnology, Hamdard University, Delhi, India. After completion of his M.Sc. program, he joined the ICGEB, New Delhi as Pre-doctoral fellow and focused his research on understanding the mismatch repair complex of malaria parasite. His finding revealed many interesting facts about the MMR pathway and their associated components. He had characterized the first eukaryotic UvrD helicase from Plasmodium falciparum. He had also been part of the several research teams to study the Plasmodium falciparum DOZI (DDX6 Helicase), Plasmodium falciparum MLH, Werner (WRN) helicase, BLOOM (BLM) helicase, RuvB1 helicase, XPD helicase, XPB helicase, UvrD helicase, and several plant helicases like Oryza sativa BAT1, Oryza sativa SUV3 and Pisum sativum. Recently he focused to identify the inhibitor molecule of the helicases of therapeutic importance like UvrD helicase and PfRuvB1. Currently his work is focused to identify the inhibitor molecule of PfMLH protein. Considering the previous and current finding about PfMLH and PfUvrD, it seems that targeting their interaction and or their biochemical activities may emerge as suitable therapeutic target for the control of malaria.
Currently, he had published 13 peer reviewed original research publications and several abstracts in National and International meeting and conferences.
Research Interest
Molecular Biology and parasitology