Michael A. LiewResearch & Development Scientist, Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, Utah, USA
Biography
My research interests have taken a ?Jack of all trades, master of none? approach. During my undergraduate degree at Monash University (Australia), I started doing measuring the avidity of autoantibodies using a chaotropic agent and enzyme linked immunsorbent assay (ELISA). I received my PhD from the University of Wollongong (Australia) studying the cellular expression of plasminogen activator inhibitor type 2. I worked for a year on a pre-doctoral fellowship at the University of California San Francisco (UCSF, USA) measuring the diffusion of small solutes in the cytoplasm of human erythrocytes using a technique called fluorescence recovery after photobleaching (FRAP). During the first 2 years of my post-doctoral research at the University of Utah (USA), I worked on examining the loss of heterozygosity (LOH) in the disease neurofibromatosis type 1 (NF1). My current position is a research and development scientist in the Institute for Clinical and Experimental Pathology at ARUP Laboratories (USA). I have worked on DNA genotyping by high resolution melting as well as improving diagnostic assays that use flow cytometry for diagnostic purposes. However, for the past 2 years I have been upgrading some of our tissue fluorescence in situ hybridization (FISH) from a manual analysis method to a digital analysis method.