Department of Orthopedics, University of Maryland School of Medicine, USA
Dr. Gupta is a Research Associate faculty of the school of Medicine at University of Maryland, Baltimore. She completed her doctorate degree in Organic Chemistry Ã¢â¬âNatural products isolation and characterization. She earned her spot as Post-doctoral fellow at the University of Maryland. She published scientific results in very reputed journals and presented at international conferences. Dr. Gupta moved to orthopedics department, Maryland, where she was offered Research Associate position at UMB. In addition to research, Dr. Gupta is a regular contributor to train students, fellows and exchange program international fellows. Dr. Gupta has reviewed the publications in India and now with her mentor. She recently collaborated on a manuscript with friend and colleague. She currently resides in Maryland with her family.
Research Interest: My academic and research training have provided me diverse background in a wide variety of scientific disciplines including organic chemistry, molecular biology, biochemistry and cancer biology. These distinct experiences have contributed to pursue my carrier as an independent research investigator. Specially, I found my more passion to be in the area of bone biology research. The possibility of improving joint pain in bone and bone metastasis in cancer challenge of basic research is both rewarding and motivating. My recent research interest focuses on the effects of bone related disease such as osteoarthritis, rheumatoid arthritis, and prostate cancer - bone metastasis. During my post-doctoral training, I have learned many techniques, obtained skills, and generated the drive and passion necessary for bone biology research. My research project will be focus on following 1) stem cell behavior including cell differentiation and migration and signaling pathways involved in this process. 2) Due to the limited effectiveness of available medication for osteoarthritis (OA) and rheumatoid arthritis (RA), much interest has been placed in exploring phytochemical research. Such as Curcumin is the most active constituent of the plant Curcuma Longa (Turmeric), which has been demonstrated to have anti-inflammatory, anti-oxidative and pro-apoptotic in animal models, as well as human trials. However, the exact mechanisms of the role of curcumin in bone pain prevention and modulation are yet to be determined. My research focus is to identify a chemo-preventive strategy that can restores a healthy mobility in human joint pain bone by dietary addition and stem cell based tissue engineering for clinical bone formation.