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EuroSciCon Conference on Virology and Infectious Diseases
April 22-23, 2019 | Athens, Greece
Page 40 Archives of Clinical Microbiology
ISSN: 1989-8436 Virology and Infectious Diseases 2019
Multi-drugs resistance among pathogenic bacteria is menaced in the
recent past. Bacteria exposed to xenobiotics at sub-lethal concentration
develop resistance through nonspecific hydrolysis of antibiotics. Soil
isolates Bacillus cereus showed resistance against chloramphenical,
monochrotophos, ampicillin, cefotaxime, streptomycin and tetracycline.
Multi-drug resistant properties of this particular strain have been confined
to the plasmid, which was verified using plasmid curing by exposing to
2% sodium dodecyl sulfate and were able to resume multi-drug resistance
properties once the plasmid was transformed back to bacteria. Further
the plasmid DNA was sequenced on MiSeq using 2x300 bp chemistry to
generate approximately 1 GB of data. The Draft assemblies of short Illumina
sequence reads (2x300 Mi-Seq library) was analyzed by 4200 tape station
system. The presence of hydrolases and hypothetical proteins suggest that
the plasmid is capable of degrading antibiotics and thus responsible for
multi-drug resistance.
Cross resistance is the cause for
multi-drug resistance among soil
flora
A Murugan
Periyar University, India
Biography
He is the Associate Professor, Department of Micro-
biology, Periyar University. Previously he was work-
ing as lecturer in the Department of Microbiology
andasa lecturer in theDepartmentofBiotechnology
in Muthayammal College of Arts and Science.
A Murugan, Arch Clin Microbiol 2019, Volume:10
DOI: 10.4172/1989-8436-C1-016