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Page 62

May 24-25, 2018

London, UK

Vascular Surgery 2018

3

rd

Edition of World Congress & Exhibition on

Vascular Surgery

Journal of Vascular and Endovascular Therapy

ISSN: 2573-4482

BACKGROUND:

The endovascular treatment of peripheral arterial

occlusive disease (PAOD) has undergone rapid evolution during

the last years, characterized by the availability of a plethora of

new devices and techniques that make an increasing number of

lesions (technically) amenable to an “endo-first” approach. The

interventionalist is now confronted with a multitude od options to

cross and treat a lesion, but surprisingly little scientific evidence

exists as to which method should be preferred over another, and

in which lesion. For example, the notion that primary nitinol stents

are superior to balloon angioplasty is based solely on three RCTs,

the superiority of drug eluting stent over bare stent on a subgroup

in one RCT, and the difference between drug-eluting balloons and

nitinol stenting has never been addressed in an RCT.

LEARNING OBJECTIVES:

This course will provide an overview of

available endovascular techniques, including balloon angioplasty,

bare stent implantation, stentgrafts, drug-eluting balloons, and

drug-eluting stents. Region by region, the available literature

concerning experience, expected primary patencies, and

comparisons (where available) between the available methods

will be appraised. Questions for which evidence is urgently needed

but not available will be defined. For each region, a decision tree

based upon the available evidence will be drafted and opened for

discussion.

The following techniques will be covered:

• Balloon angioplasty

• Bare nitinol stents

• Drug-eluting stents

• Sentgrafts

• Drug-eluting balloons

Recent Publications

1. Self-expanding nitinol stents of high versus low chronic

outward force in de novo femoropopliteal occlusive

arterial lesions (BIOFLEX-COF trial): study protocol for

a randomized controlled trial. Wressnegger A, Kaider

A, Funovics MA. Trials. 2017 Dec 14;18(1):594. doi:

10.1186/s13063-017-2338-0.

2. Paclitaxel-Eluting Balloon Versus Standard Balloon

Angioplasty in In-Stent Restenosis of the Superficial

Femoral and Proximal Popliteal Artery: 1-Year Results

of the PACUBA Trial. Kinstner CM, Lammer J, Willfort-

EhringerA,MatzekW, GschwandtnerM, JavorD, Funovics

M, Schoder M, Koppensteiner R, Loewe C, Ristl R, Wolf F.

JACC Cardiovasc Interv. 2016 Jul 11;9(13):1386-92. doi:

10.1016/j.jcin.2016.04.012.

3. Treatment of the aorto-iliac segment in complex lower

extremity arterial occlusive disease. Wressnegger A,

Kinstner C, FunovicsM. J Cardiovasc Surg (Torino). 2015

Feb;56(1):73-9. Epub 2014 Dec 5.

4. Endovascular repair of thoracoabdominal aortic

aneurysms with a novel multibranch stent-graft design:

preliminary experience. Kinstner C, Teufelsbauer H,

NeumayerC, DomenigC,WressneggerA,Wolf F, Funovics

M. J Cardiovasc Surg (Torino). 2014 Aug;55(4):543-50.

Epub 2014 Jul 10.

5. [Endovascular interventions for multiple trauma].

Kinstner C, Funovics M. Radiologe. 2014 Sep;54(9):893-

9. doi: 10.1007/s00117-013-2638-7. German

Biography

Martin Funovics is an interventional radiologist and has been working in all

fields of endovascular treatment and oncologic IR for over 20 years. He has

authored over 90 peer-reviewed publications both in clinical IR as well as

in basic research in vascular and tumor biology. He has co-developed nov-

el stent graft designs for aortic repair and performed several first-in-man

procedures of novel devices. He is PI of the first (ongoing) RCT assessing

chronic outward force between different nitinol stents in peripheral arterial

disease.

martin.funovics@meduniwien.ac.at

Endovascular treatment of peripheral arterial disease in 2018:

Which technology to use, and why

Martin A Funovics

Medical University of Vienna, Austria

Martin A Funovics, J Vasc Endovasc Therapy 2018, Volume 3

DOI: 10.21767/2573-4482-C1-002