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Volume 4 Journal of Pediatric Care
ISSN: 2471-805X
Page 28
Notes:
August 06-07, 2018 Madrid, Spain
&
JOINT EVENT
2nd Edition of International Conference on Adolescent Health & Medicine
18th International Conference on Pediatrics Health
Pediatrics Health 2018
&
Adolescent Health 2018
August 06-07, 2018
Quantitative assessment of renal heterogeneity and echogenicity in healthy pediatric patients using a
novel protocol
S ignificant differences exist in renal heterogeneity in patients with congenital ureteropelvic obstruction who underwent
pyeloplasty compared to the unaffected contralateral kidney. As a validation, we sought to determine normal heterogeneity
as measured by heterogeneity index (HI) in normal kidneys of children. This novel evaluation may elucidate the subtle changes
in echogenicity seen in children over the first year of life. We reviewed kidney images in children performed with non-
nephrologic, non-urologic disease. Each image was evaluated by a novel program which converts pixels in a gray-scale US to a
binary map to produce HI values. We performed univariate analysis comparing HI in 2 groups: left versus right kidney (against
spleen and liver), and patients aged <1 year old versus greater or equal to 1 year old. 122 sonograms were available for analysis.
The average age was 4.7 and standard deviation (SD) 5.4 years old. Overall, the average HI was 1.17. The average HI of the
right kidney was 1.19 (n=37, SD 0.12) and the left kidney was 1.167 (n=37, SD 0.10) with no statistically significant difference
between sides (p = 0.2). Mean HI in those <1 years was 1.15 (n=36, SD 0.09) and 1.17 (n=36, SD 0.12) in those greater or equal
to 1 year old. No difference was observed between the groups on univariate analysis (p = 0.4). While renal echogenicity is
enhanced in patients less than 1 year old, the change to normal echogenicity appears to be homogenous as there is no change
in overall HI between patients greater or less than 1 year old.
Biography
Dr. Ghorayeb has completed his PhD jointly between Iowa State University and the University of Iowa. He is Professor of Radiology and Molecular Medicine, and Professor
of Biomedical and Electrical Engineering at Hofstra University. He has published over 100 papers in reputable journals, conferences, and invited presentations and has
been serving as primary reviewer at NIH, and as an editorial board member of AIUM, JTU, and IEEE.
Sleiman R Ghorayeb
Hofstra University, USA
Sleiman R Ghorayeb, J Pediatr Care 2018, Volume 4
DOI: 10.21767/2471-805X-C3-010