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PCOS 2018 Journal of Clinical and Molecular Endocrinology
ISSN: 2572-5432 Page 50
June 07-08, 2018
London, UK
4th World Congress on
Polycystic Ovarian
Syndrome
Introduction: The majority of intracytoplasmic sperm injection
(ICSI) cycles lead to the transfer of embryos to the uterus, in cases
of polycystic ovary syndrome (PCOS) but some do not implant.
Thus, the main cause of failure in IVF is implantation failure.
Repeated failure in vitro-fertilization treatment is frustrating to
patients and doctors. Patients with good quality embryo pose a
special therapeutic challenge (consecutive embryo transfer).
Objectives: To examine whether consecutive transfer of embryos
on day three and on day five improves ICSI success rates in PCOS
with multiple consecutive implantation failures.
Study Design: This is a randomized controlled clinical trial
including 50 patients, randomly distributed into two groups:
Group A (The study group) consists of 25 patients subjected to
consecutive (double) embryo transfer at day three and at day five.
Group B (The control group): consists of 25 patients subjected to
embryo transfer at day five.
Results: There was statistical non-significant difference of age,
cause of infertility, number of previous trials, oocyte retrieved,
embryos available andmultiple pregnancies. Therewas statistical
significant difference of pregnancy rate and clinical pregnancy
rate in two groups (54% to 34%).
Conclusion: For PCOS patients with repeated ICSI-embryo
transfer failures, sequential transfer on day three and day five
may improve the clinical pregnancy rate in cases of repeated
implantation failure as longas good-quality embryos are available.
Impact of consecutive embryos transfer in PCOS repeated
implantation failure cases
Asem Anwar Abdou Moussa
Egypt
J Clin Mol Endocrinol 2018, Volume 3
DOI: 10.21767/2572-5432-C1-003