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E u r o S c i C o n C o n f e r e n c e o n
Neurology & Neurological
Disorders
Neurology 2018
J u l y 1 2 - 1 3 , 2 0 1 8
P a r i s , F r a n c e
Page 70
Journal of Neurology and Neuroscience
ISSN: 2171-6625
C
hronic cerebral ischemia (CCI) is a form of chronic progressive
cerebrovascular disease characterized by multifocal or diffuse
brain damage and is manifested in the form of complex neurological
and neuropsychological disorders. The main manifestations of CCI
are impairment of cognitive (recognition) function, affective disorders
and movement disorders polymorphic. The main etiological factor of
cerebral microangiopathy is hypertension, which causes arteriosclerosis
(lipogialinoz) of small penetrating arteries and arterioles. Although patients
with CCI prefer to focus on such subjective symptoms like headache,
dizziness, tinnitus, fatigue, the core clinical CCI determining the severity
of the condition of patients is increasing restriction of neuropsychological,
motor functions. The result of neuropsychological disorders in CCI is the
development of vascular dementia. We observed 766 people (300 women,
466 men; mean age 65±105 years), held in-patient treatment in the Clinical
Hospital of Tashkent in the period from November 2013 to December
2015. All patients were followed-up visit, which included a neurological
examination: ECG, Doppler ultrasound, EEG and a set of neuropsychological
tests. Patients were divided into two groups: I group consists of standard
therapy of CCI + nitrendipine 10-40 mg / day + alzepil 5 mg/day at morning
6 months. II group consists of CCI standard therapy. Repeated study of
patients had clinically significant achievement of target blood pressure, as
well as significantly improvement of cognitive functions in the first group
of patients. There were 4 cases of stroke during the next two years in the
first group of patients (atherothrombotic origin). In the second group of
patients there were 19 cases of stroke, 3 of them repeated. Use of the
drug nitrendipine for the correction of blood pressure in elderly patients
significantly lowers the risk of stroke and gross cognitive impairment
Prevention of stroke in patients with chronic cerebral ischemia
in the background of isolated systolic hypertension
M A Bakhadirova, S O Bahadirov, M O Alimukhamedova and D Kh
Akilov
Neurorehabilitation Department, Tashkent Institute of Postgraduate Medical Education, Uzbekistan
M A Bakhadirova et al., J Neurol Neurosci 2018, Volume: 9
DOI: 10.21767/2171-6625-C1-009
Biography
Munisa Bakhadirova has graduated fromTashkent Medical Institute (1988
– 1994) and completed her Residentship in Neurology (1994 – 1996) at
Tashkent Medical Institute. In 2002 she completed her PhD on Rates of
cerebrovascular flow at different stages of stroke rehabilitation. Since 2004
she has been an Assistant Professor, Neurerehabilitation department,
Tashkent Institute of Postgraduate medical education.
akilov.dj@gmail.com