neurology-2018-posters-abstracts

t h

E u r o S c i C o n C o n f e r e n c e o n

Neurology & Neurological

Disorders

Neurology 2018

J u l y 1 2 - 1 3 , 2 0 1 8

P a r i s , F r a n c e

Page 65

Journal of Neurology and Neuroscience

ISSN: 2171-6625

eurodegeneration with brain iron accumulation (NBIA) consists

of various genetically and clinically distinct forms of progressive

motor disorders characterized by iron accumulation in the specific

regions of the central nervous system. The most common subtype of

this spectrum is pantothenate kinase-associated neurodegeneration

(PKAN). The typical magnetic resonance imaging pattern called eye-

of-the-tiger is seen in most of the patients with PKAN and basically it

has two distinct forms, early onset rapidly progressive (classical) and

late onset slowly progressive (atypical). The common presentation of

patients with classical PKAN is dystonia with dysarthria and rigidity

in the first decade of life. Our PKAN family members presented with

night blindness as the initial symptom without developing dystonia for

a while. Night blindness due to retinal involvement can be seen in the

course of the disease but it is rare as the initial symptom in classical

PKAN so it should be kept in mind.

Conclusion:

This case study shows that classical PKAN patients can

present with night blindness without developing other symptoms. We

wanted to emphasize this kind of presentation

A PKAN family presenting with night blindness as the initial symptom

Gokalp Arif Utkugun¹, Ozge Uygun², Nihan Hande Akcakaya³

and Zuhal Yapıcı²

¹Yeditepe University, Istanbul, Turkey

²Istanbul University, Istanbul, Turkey

³ASDETAE, Istanbul University, Istanbul, Turkey

Biography

Gokalp Arif Utkugün has graduated from Cağaloğlu Anadolu High

School in 2013. Since 2013 he has been studying medicine in Yeditepe

University Faculty of Medicine. He speaks English and German. He

is interested in General Surgery, Plastic and Reconstructive Surgery,

Pharmacology, Neurology, Neuroscience and History of Medicine. He

passed USMLE Step1 in 2017. In Jul’ 2016 he did Observership at Plastic

and Reconstructive Surgery in Vilnius, Lithuania. In Apr’2018, he attended

New Era of Medicine congress in Istanbul.

Gokalp Arif Utkugun et al., J Neurol Neurosci 2018, Volume: 9

DOI: 10.21767/2171-6625-C1-009