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Mass Spectrometry 2019

March 04-05, 2019

Berlin, Germany

Mass Spectrometry

9

th

Edition of International Conference on

International Journal of Drug Development and Research

ISSN: 0975-9344

Page 23

Removal of interferences in ICP/MS using

deuterium as a collision gas

Yong-Nam Pak

and

Seoyoung Lee

Korea National University of Education, South Korea

T

he use of collision cell in ICP/MS has brought the

removal of isobaric interferences in Ar ACP/MS

especially for the species related to Ar background

such as Ar dimers and Ar related molecular species.

Determination of Fe or Se has been limited because of

those interferences. However, the use of collision cell can

eliminate or reduce molecular interferences. Hydrogen

or Helium has been used as a collision gas. Different

approaches such as reaction cell could be introduced

instead of collision by using more reactive gases such

as ammonia. However, the introduction of hydrogen in

the collision cell does react with sample elements and

produce molecular species to some degree. Matrix such

as Br could react with hydrogen to make BrH to interfere

on the determination of Se. The use of deuterium can

alleviate this problem. The accuracy and precision could

be improved by the use of deuterium especially for the

complex matrix samples. Details of the improvement

of complex matrixed sample such as oyster will be

discussed.

Biography

Yong-Nam Pak has completed his PhD in Analytical Chemis-

try by University of Missouri. He has worked as Professor of

Department of Chemistry at Korea National University of Edu-

cation. He has published more than 80 papers in reputed jour-

nals and has serving as a Vice President of Korea Analytical

Science and Technology.

pakyn@knue.ac.kr

Yong-Nam Pak et al., Int J Drug Dev & Res 2019, Volume 11

DOI: 10.21767/0975-9344-C1-005