Mass Spectrometry 2019
March 04-05, 2019
Berlin, Germany
Mass Spectrometry
9
th
Edition of International Conference on
International Journal of Drug Development and Research
ISSN: 0975-9344
Page 23
Removal of interferences in ICP/MS using
deuterium as a collision gas
Yong-Nam Pak
and
Seoyoung Lee
Korea National University of Education, South Korea
T
he use of collision cell in ICP/MS has brought the
removal of isobaric interferences in Ar ACP/MS
especially for the species related to Ar background
such as Ar dimers and Ar related molecular species.
Determination of Fe or Se has been limited because of
those interferences. However, the use of collision cell can
eliminate or reduce molecular interferences. Hydrogen
or Helium has been used as a collision gas. Different
approaches such as reaction cell could be introduced
instead of collision by using more reactive gases such
as ammonia. However, the introduction of hydrogen in
the collision cell does react with sample elements and
produce molecular species to some degree. Matrix such
as Br could react with hydrogen to make BrH to interfere
on the determination of Se. The use of deuterium can
alleviate this problem. The accuracy and precision could
be improved by the use of deuterium especially for the
complex matrix samples. Details of the improvement
of complex matrixed sample such as oyster will be
discussed.
Biography
Yong-Nam Pak has completed his PhD in Analytical Chemis-
try by University of Missouri. He has worked as Professor of
Department of Chemistry at Korea National University of Edu-
cation. He has published more than 80 papers in reputed jour-
nals and has serving as a Vice President of Korea Analytical
Science and Technology.
pakyn@knue.ac.krYong-Nam Pak et al., Int J Drug Dev & Res 2019, Volume 11
DOI: 10.21767/0975-9344-C1-005




