Archives in Cancer Research

Biotechnology QC Specialist at Arven Ä°laç, Istanbul, Turkey

Zeynep Bor is serving at an esteemed academic position in Biotechnology QC Specialist at Arven Ä°laç, Istanbul, Turkey. She is the recipient of numerous awards for her expert research works in related fields. Her research interests in For instance, valproic acid has been shown to be related to apoptosis pathway and induced the suppression of C6 glioma cell migration,Zonisamide is also commonly used as an antiepileptic drug because of its scavenging effects on hydroxyl and nitric oxide radicals, Due to valproic acid’s anticancer activity, zonisamide was investigated for its antiproliferative and antioxidant effects on C6 glioma cells, Zonisamide: Antiproliferative and Antioxidant Effects on C6 Glioma Cancer Cell Model.

Zonisamide: Antiproliferative and Antioxidant Effects on C6 Glioma Cancer Cell Model

1. Seizures are often seen in patients with brain tumors and antiepileptic drugs such as acetazolamide, valproic acid.
2. Some of these antiepileptic drugs also have anti-cancer effects that have been shown in many studies.
3. For instance, valproic acid has been shown to be related to apoptosis pathway and induced the suppression of C6 glioma cell migration.
4. Zonisamide is also commonly used as an antiepileptic drug because of its scavenging effects on hydroxyl and nitric oxide radicals.
5. Due to valproic acid’s anticancer activity, zonisamide was investigated for its antiproliferative and antioxidant effects on C6 glioma cells.
6. The percentage of cell viability, measurement of DNA synthesis, superoxide dismutase activity and the measurement of glutathione were studied in the presence of zonisamide.
7. Using of zonisamide with anti-cancer agents fighting against glioma cells might be useful because of its antiproliferative effects.