Jennifer A. Doll

Jennifer A. Doll
Associate Professor in the Department of Biomedical Sciences, University of Wisconsin Milwaukee.USA.
 
Biography
Dr. Doll received her Ph.D. in Molecular Genetics at Washington University, conducted a post-doctoral fellowship in the tumor angiogenesis at Northwestern University, and is currently an Associate Professor in the Department of Biomedical Sciences at the University of Wisconsin Milwaukee. Since 1993, her research focus has been prostate cancer (PCa). In particular, she has focused on two tumor suppressor proteins, pigment epithelium derived factor (PEDF) and thrombospondin-1 (TSP-1), both of which are potent anti-angiogenic agents. Interestingly, both also function in regulation of lipid metabolism. Obesity has reached epidemic levels in the United States, affecting nearly 30% of the population, and it is evident that excess adipose tissue fuels PCa. However, the molecular mechanisms contributing to obesity-driven PCa are largely unknown. Dr. Doll?s research focuses on understanding how the functions of PEDF and TSP-1 are altered in an obese PCa microenvironment, with the goal of identifying novel targets for PCa therapy.
 
Research Interest
Dr. Doll?s research focuses on understanding how the functions of PEDF and TSP-1 are altered in an obese PCa microenvironment, with the goal of identifying novel targets for PCa therapy.