Dr. Kuladip Jana

Dr. Kuladip Jana
Senior Scientist, Division of Molecular Medicine and Scientist In-charge of the Centre for Translational Animal Research, Bose Institute, Kolkata, India
 
Biography
Dr. Kuladip Jana, M.Sc., M.S., Ph.D. is presently serving as a Senior Scientist in the Division of Molecular Medicine and Scientist In-charge of the Centre for Translational Animal Research, Bose Institute, Kolkata, India. Dr. Jana was trained as a Post-doctoral Research Associate in Molecular Endocrinology and Reproduction in relation with Aging in Garrison Institute on Aging, Texas Tech University Health Sciences Centre, Texas, U.S.A. and in Vaccine development against Cholera and Typhoid in National Institute of Cholera & Enteric Diseases, Kolkata and also served as a Visiting Scientist in the field of Molecular signalling regulating cell growth/survival and death/apoptosis in cancer cells at Saha Institute of Nuclear Physics, Kolkata after obtaining his M.S. and Ph.D. in Reproductive Medicine from an Indian University.
 
Research Interest
Presently, my interest focusing on Translational animal research in the diverse directions i.e. Molecular signalling of germ cell/ Leydig cell apoptosis by Benzo(a)pyrene and its protection by natural aryl hydrocarbon receptor (AhR) antagonist, Molecular Mechanisms of Germ-line Stem Cell Regulation: Special emphasis on Diabetes and aging, Ageing associated oxidative stress & testicular gametogenic and steroidogenic disorders: ameliorating potential of natural antioxidants, Resveratrol Induced Apoptosis in Cervical and Breast Cancer Cells: role of ?- catenin and Wnt signalling, Sulforaphane inhibits Akt mediated GSK3? and FoxO3a signaling and triggers apoptosis in breast cancer. Development of nanoparticle mediated treatment strategy to target NOTCH1 in triple negative breast cancer (TNBC) Xenograft model, Testicular carcinogenesis in relation with steroidogenesis and StAR protein expression: role of MAPKs, Novel anti-filarial and anti-cancer drug development from natural resources and to search the link between Polycystic Ovary Syndrome and both Type 1 and Type 2 Diabetes Mellitus as well as mechanism of wound healing by Calendula officinalis in diabetic condition.