neurology-2018-posters-abstracts

t h

E u r o S c i C o n C o n f e r e n c e o n

Neurology & Neurological

Disorders

Neurology 2018

J u l y 1 2 - 1 3 , 2 0 1 8

P a r i s , F r a n c e

Page 105

Journal of Neurology and Neuroscience

ISSN: 2171-6625

ecent animal studies have revealed that the gut microbiota has much wider effects on host physiology and development than

originally believed, including the early-life programming of brain circuits involved in the control of emotions, motor activity,

and social behavior. The current challenge is to understand the precise molecular mechanisms mediating the communication

between the microbiota and the brain. In this presentation, I will cover new evidence from my laboratory suggesting that the

central activation of pattern recognition receptors by bacterial peptidoglycan fragments could be one of the signaling pathways

mediating the communication between microbiota and the developing brain.

Bacterial peptidoglycans as novel signaling

molecules from microbiota to brain

Rochellys Diaz Heijtz

Karolinska Institutet, Solna, Sweden

J Neurol Neurosci 2018, Volume: 9

DOI: 10.21767/2171-6625-C1-009