RIKEN Structural Biology Laboratory
Yokohama Institute,Yokohama City, Japan
I born and brought up from southern part of India, Pudukkottai, Tamil
Nadu. I completed my school education in my home down and graduated
from University of madras, India in 2000. I was started working as postdoctoral fellow at AIST, Japan as soon as I submitted my thesis work and continued till got the tenured position in April 2005. From 2005 onwards I am working for RIKEN as a Research Scientist and in 2008 promoted as Senior Scientist.
Our laboratory is interested in the structure and function of the
macromolecules, specifically transcription-related molecules (proteinnucleic
acid interactions) which includes RNA/DNA binding proteins, RNA
polymerase and eukaryotic chromatins. In our lab, we use X-ray
crystallographic techniques to investigate the structures of
macromolecules involved in gene transcription. We also use biophysical
and biochemical methods to understand structure-function relationships.
Currently, our focus of the lab is to understand the structural and
functional analysis of archaeal and eukaryotic RNA polymerase through
X-rays / Cryo-EM.