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Volume 4
Clinical Pediatric Dermatology
ISSN: 2472-0143
Page 18
Notes:
October 15-16, 2018 Rome, Italy
&
JOINT EVENT
14
th
International Conference on
Clinical Dermatology
5
th
International Conference on
Advances in Skin, Wound Care and Tissue Science
Wound Congress 2018 &
Clinical Dermatology Congress 20
18
October 15-16, 2018
Regina Folster-Holst
University Medical Center Schleswig-Holstein, Germany
Regina Folster-Holst, Clin Pediatr Dermatol 2018, Volume 4
DOI: 10.21767/2472-0143-C2-004
Epidermal barrier structure and function in atopic dermatitis and ichthyosis
T
he clinical phenotype of atopic dermatitis (AD) results from complex interactions between genetic and environmental
factors, which influence the epidermal structure and function, as well as the immune system. In addition, neurogenic
disturbances and loss of the diversity of microbiome (intestinal and cutaneous) are causes of exacerbation. Epidermal barrier
defects seem to be a hallmark of pathogenesis of AD. The quality of the skin barrier can be assessed by using a new semi-
quantitative method to measure intercellular lipid lamellae. This procedure was used to evaluate the influence of emollients and
also the topical application of drugs like corticosteroid and calcineurin inhibitors.
Biography
Regina Folster-Holst completed her PhD in 1984 from Christian-Albrechts-University, Kiel, Germany. After a Medical Assistant time in a children's clinic for Cystic Fibrosis
and Allergy at Amrum, Germany, she began her specialist training for dermatologists at the Department of Dermatology, Kiel, Germany, in November 1985. In 1992,
she was recognized as a Specialist in Dermatology and Allergology. Her habilitation was in 2003, at the Medical Faculty of the Christian-Albrechts-University of Kiel and
the appointment as a Professor took place in 2007. Since 1992, she works as a Senior Physician at the University Medical Center Schleswig-Holstein, Department of
Dermatology in Kiel, Germany. Clinical activity and research are priority for her, primarily in the area of Atopic Dermatitis, Pediatric Dermatology, Exanthems in Childhood
and Parasitosis.
rfoelsterholst@dermatology.uni-kiel.de