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E u r o S c i C o n C o n f e r e n c e o n

PEDIATRICS

2017

Journal of Pediatric Care

ISSN 2471-805X

N o v e m b e r 1 3 - 1 4 , 2 0 1 7

L o n d o n , U K

Pediatrics 2017

Volume:3 Issue:4(Suppl)

Page 20

Background:

Clinical guidelines recommend intensive community treatment to

reduce dependency on adolescent psychiatric inpatient care, but no such provision

in the UK has been evaluated in a randomised controlled trial (RCT). We designed a

supported discharge service (SDS), an intensive community treatment team, and

compared this with treatment as usual (TAU).

Methods:

106 patients younger than 18 years were admitted for inpatient care and

randomised (1:1) to either SDS or TAU. Intention-to-treat primary outcomes were

inpatient bed days, Strengths and Difficulties Questionnaire (SDQ) and Children’s

Global Assessment Scale (CGAS). Cost effectiveness was explored in terms of

CGAS scores and quality adjusted life years based on the EQ-5D-3L, taking a

health and social care perspective.

Findings:

At six-month follow-up, there was a significant decline in hospital use

among patients randomised to SDS in unadjusted analyses (mean 47.25) vs

TAU (mean 84.32). The ratio of mean total of inpatient days of TAU to SDS was

1.67 (95% CI: 1.02 to 2.81), t (101) = 2.08, p=.04. However, in adjusted analyses,

considering baseline differences in inpatient bed days, treatment difference on the

log scale was no longer significant (-.05, 95%CI: -1.02 to .01, p=0.057). There were

no significant differences in SDQ, CGAS or treatment satisfaction. SDS patients

were significantly less likely to report multiple episodes of self-harm (OR = .18,

95% CI: .05 to .64) and more likely to reintegrate to community schools (.81 SDS

vs .51 TAU, OR= 4.14, 95% CI: 1.73 to 9.92). There was no evidence of differential

effect in patients with psychosis, severe disability or patients fromminority ethnic

groups. Cost-effectiveness acceptability curves based on both the CGAS and

QALYs suggested there was at least a 50% probability of SDS being cost effective.

Interpretation:

The addition of SDS to adolescent inpatient care and standard

outpatient follow-up improved school reintegration and lowered the risk of

multiple self-harm. There is an implication of reduced bed usage at six-month

follow up, but this did not reach statistical significance after adjusting for baseline

differences. There were no differences in other clinical, functional and patient

satisfaction outcomes.

Biography

Dennis Ougrin graduated from a Medical School in Ukraine

in 1998 and underwent post-graduate training in England. He

completed his higher training in Child and Adolescent Psychi-

atry at Guy’s and Maudsley and is currently a Consultant Child

and Adolescent Psychiatrist leading Supported Discharge Ser-

vice at South London and Maudsley NHS Foundation Trust. He

is also a Clinical Senior Lecturer at the Institute of Psychiatry,

Psychology and Neuroscience. He leads a programme of infor-

mation exchange between the UK and Ukraine. His main pro-

fessional interests include prevention of Borderline Personality

Disorder and effective interventions for self-harm. He is the au-

thor of Therapeutic Assessment, a novel model of assessment

for young people with self-harm. He is the Chief Investigator of a

randomised controlled trial of Supported Discharge Service ver-

sus Treatment as Usual in adolescents admitted for in-patient

care and a Principal Investigator of a randomised controlled

trial comparing intensive mental health intervention versus usu-

al social care in Looked After Children. He is also working on

developing a modular psychotherapeutic intervention for self-

harm and on understanding the pathophysiology of self-harm

in young people

dennis.ougrin@kcl.ac.uk

Intensive Community Treatment

versus Usual Treatment for

Adolescents Admitted to Inpatient

Care: a Randomised Controlled Trial

Dennis Ougrin,

King’s College London, UK

Dennis Ougrin, J Pediatr Care 2017, 3:4(Suppl)

DOI: 10.21767/2471-805X-C1-001