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Volume 3, Issue 4 (Suppl) J Clin Exp Orthop
ISSN:2471-8416 Osteoporosis and Arthroplasty 2017
December 04-05, 2017
&
11th International Conference on
Joint Event
OSTEOPOROSIS, ARTHRITIS & MUSCULOSKELETAL DISORDERS
December 04-05, 2017 | Madrid, Spain
10th INTERNATIONAL CONFERENCE ON ARTHROPLASTY
Zeayd Saeed et al., J Clin Exp Orthop 2017, 3:4(Suppl)
DOI: 10.4172/2471-8416-C1-003
Vitamin D or exercise whilst on high fat diet normalise bone mineral density
Zeayd Saeed1, 2, Justyna Janus2, J Barratte2 and Cordula Stover2
1Al-Furat Al-Awsat Technical University, Iraq
2University of Leicester, UK
Diet induced obesity is a major health problem in developed and developing countries and affects not only cardiovascular but
also skeletal health. Lipids have a direct reducing impact on bone mineral density by inhibiting osteoblastic differentiation
and enhancing osteoclast differentiation. Conversely, vitamin D or exercise enhances the bone mineral microarchitecture through
activating the osteoblasts activity and increasing the deposition of calcium. The effect of vitamin D or exercise on bone mineral
density during high fat feeding was studied in male and female C57Bl/6J mice by micro-computed tomography. Experimental mice
received a high fat high sugar diet with additional vitamin D supplement or had access to voluntary exercise. After five weeks, they
were compared to mice on high fat high sugar diet. We find that vitamin D supplementation or additional exercise normalize within
five weeks the bone mineral density by correcting the cortex and trabeculae segmentations. We conclude that these two intervention
modes may be of value to obese persons who are in the process of correcting their dietary habits.
Biography
Zeayd Saeed has been graduated from the college of Veterinary Medicine and Surgery of Al-Qadisiyah University, Iraq as Veterinary Doctor. Later on, he obtained
his Post-graduation in Microbiology from Belarusian State University, College of Biology, Belarus and then started working as Assistant Lecturer at the University of
Al-Furat Al-Awsat Technical University / Technical institute of Samawa, Nursing department, Iraq. Presently he has been standing as a PhD student at the University
of Leicester in Leicester City, UK.