22 / 22
Pain Management 2018
Internal Medicine 2018
International Journal of Anesthesiology & Pain Medicine
ISSN: 2471-982X
Page 50
March 26-28, 2018
Vienna, Austria
JOINT EVENT
7
t h
E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Internal Medicine and Patient Care
&
6
t h
E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Pain Management
Volume 4
Background:
Cerebral palsy is a common pediatric problem
encountered in about 1:3 per 1000 born children and causing
variablemental,motor andbehavioral dilemmas.Newlyintroduced
trials of neurogenesis with different agents are now extensively
evaluated.
Objective:
Our study was conducted to evaluate the neurotrophic
response to B12 vitamin and omega-3 fatty acids in children
diagnosed early with variable forms of cerebral palsy. The
response was monitored both clinically and with CT scan as being
a highly predictive tool for assessing cerebral palsy.
Design:
The study was carried out on 40 cerebral palsy patients;
26 (65%) out of them weregirls, and 14 of them were boys, aged
from 0 to 5 years old; from outpatient clinic at Zakho/Duhok
General Hospital in Kurdistan Region-Iraq. Patients were treated
and followed up to 6 months to one year. They were represented
and adjusted by full history taking and clinical examination. Brain
CT scans were done for every patient to assess the degree of
brain atrophy before starting this combined therapy, and every
month for six months to one year. There was an improvement in
general health of children after interventional therapy.
Results:
The study revealed that early intervention of both omega
3 and B12 vitamin in children under 5 with cerebral palsy (cp)
shows great response based on clinical examination and CT scan
findings. Almost, after combined therapy, 80% of children with
delayed speech have very good response and improvement, 77%
of children with delayed milestone and hypertonia, and 87% with
delayed walking have positive clinical outcomes. Both sexes have
equal response to combined therapy. Such findings were obtained
as a result of early treatment and diagnosis of children with (CP).
In addition, among the treated children with CP, improvement in
CT scan results was obtained. 84% of treated children have great
improvement in their neuroimaging results frommoderate/severe
forms of brain atrophy to a mild form of brain atrophy after being
treated and followed up for 6 months - 1 year.
Conclusions:
The damaged brain sites based on CT scan
results, showed progressive improvement in response to B12
and omega-3 fatty acids upon daily supplement throughout 6
months to one year. However, combining these 2 drugs showed
preservative synergistic consequences. B12 vitamin and omega-
3 fatty acids are valuable therapy for children with various forms
of cerebral palsy particularly when being linked. The greatest
improvement in speech and motor development was significantly
observed in about 32 patients (80%) of treated children with B12
vitamin and omega- 3 fatty acids. Others have less response to
combine therapy as being presented and diagnosed beyond 1
year of age (16%).
Biography
Khajik Sirob Yaqob, MA is a specialist in childs nutrition with interest in pedi-
atric neurology. He has Associate Membership of the RCPCH; Membership
of Oxford University Hospitals and he is a Member of American Academy of
Nutrition and Dietetics; Member of Kurdistan Pediatric Society, Iraq.
khajikyaqob@yahoo.comThe positive clinical consequence of early intervention of
combined therapy (omega 3 fatty acids and B12 vitamin) on
children under 5 with variable forms of cerebral palsy
Khajik Sirob Yaqob
Kurdistan pediatric society-Iraq
Khajik Sirob Yaqob, Int J Anesth Pain Med 2018, Volume 4
DOI: 10.21767/2471-982X-C1-002