infectious-diseases-std-aids-2018-scientifictracks

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Infectious Diseases
and STD-AIDS
Infectious Diseases and STD-AIDS 2018
Journal of Transmitted Diseases and Immunity
ISSN 2471-8084
A p r i l 2 6 - 2 7 , 2 0 1 8
R o m e , I t a l y
Page 29
Background: Persistent oxidative stress, hypercatabolism, increased HIV RNA
replication and pro-inflammatory cytokines/ proteins leading to increased
demand, utilization and subsequent deficiencies of anti-oxidant micronutrients
and malnutrition are hallmarks of untreated HIV infection progression. This
research compared some indices of malnutrition such as body mass index
(BMI), hemoglobin, serum zinc, copper, and albumin among untreated HIV
infected patients and matched HIV negative healthy persons.
Materials & Methods: The BMI, hemoglobin, and serum zinc, copper, and
albumin levels of 90 antiretroviral naive adult patients attending HIV clinics in
Kaduna and Zaria were compared with age-/sex-matched HIV negative healthy
controls from the local communities. Inclusion criteria for cases and controls
were absence of pregnancy, immunosuppressive and/or psychiatric illness; in
addition to stage 1 and 2 infection, and CD4+ >500 cells/µl for patients.
Results: HIV infected patients had significantly lower BMI (25.8 kg/m2),
hemoglobin (10.0 g/dl), serum zinc (0.01 ppm), copper (-0.4 ppm), and albumin
(36.0 ppm) than BMI (27.6 kg/m2), hemoglobin (13.0 g/dl), serum zinc (0.16
ppm), copper (0.04 ppm), and albumin (39.0 ppm) of healthy controls.
Conclusion: Early stages of HIV infection, even if asymptomatic, are associated
with micronutrients deficiency and malnutrition, thus the imperative for
micronutrient supplementation in HIV infection is needed.
Biography
Obiako, Onyeadumarakwe Reginald’s area of specialty is Neu-
rology and HIV pharmacology. He has completed his Bach-
elor of Medicine and Surgery (MBBS), from University of Port
Harcourt, Choba, Port Harcourt (1987) and Master of Science
, Pharmacology) from Ahmadu Bello University Zaria
(1999). Recently he is a Doctor of Philosophy (Ph. D, Pharma-
cology with special interest in HIV), in Ahmadu Bello University
Zaria (2018).
Micronutrient deficiency among WHO stage I/II HIV infected individuals
in Kaduna and Zaria, Kaduna State: a case- control study
Obiako O. R.1, 2, Musa B. O. P. 1, 2, Hassan A1, 2, Balogun Y.2 ,
Okonkwo L.1, 2, I. Abdu-Aguye1, 2, Maiha B. B.1, 2, Muktar H. M.1, 2
and Babadoko A.1, 2
1Ahmadu Bello University, Nigeria
2Ahmadu Bello University Teaching Hospital, Nigeria
Obiako O.R. et al., J Transm Dis Immun 2018 Volume 2
DOI: 10.21767/2573-0320-C1-002